Cell Biology Worksheet - GCSE - Intermediate

Cell Biology worksheet for GCSE (Key Stage 4 / GCSE (Ages 14-16)). Intermediate level science practice, aligned to the UK National Curriculum. Print-ready with answer key included.

Science•Key Stage 4 / GCSE (Ages 14-16)•Cell Biologyintermediate

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Cell Biology: GCSE Skills in Action

Key Stage 4 (ages 14–16) · Intermediate · AQA-style

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Instructions: Work through each activity and show your reasoning in the answer spaces. Use appropriate scientific vocabulary, include units in calculations, and check that your answers address the command word.

Eukaryotic and prokaryotic cells

Use your knowledge of cell structures to answer each question. Be precise about which structures are present in each type of cell.

1. State one structure found in eukaryotic cells that is not found in prokaryotic cells.

2. Describe the function of the cell membrane.

3. Explain why a bacterial cell is described as prokaryotic.

4. Name the structure that contains genetic material in a eukaryotic cell.

Microscopy and magnification

Write your answer in the box below.

Cell division and the cell cycle

Answer in complete scientific statements where asked. Remember that mitosis produces genetically identical daughter cells and is used for growth and repair.

1. Put these stages of the cell cycle in the correct order by writing the letters: A. The cell divides; B. The DNA is copied; C. The cell grows and increases its sub-cellular structures.

2. State the number of daughter cells produced by mitosis.

3. Explain why the daughter cells produced by mitosis are genetically identical to each other.

4. Give one role of mitosis in a multicellular organism.

Transport across cell membranes

Distinguish each transport process by considering particle movement, concentration differences and whether energy is required.

1. Define diffusion.

2. Oxygen moves from a region of high concentration in the blood to a region of lower concentration in a body cell. Name the transport process.

3. Explain how active transport differs from diffusion.

4. Water moves through a partially permeable membrane from a dilute solution to a more concentrated solution. Name this process.

Investigating osmosis: analyse the data

Use the results table to answer the questions below. A positive change means the potato gained mass; a negative change means it lost mass.

Sucrose concentration (mol/dm³)	Initial mass (g)	Change in mass (g)
0.0	5.0	+1.2
0.2	5.0	+0.6
0.4	5.0	0.0
0.6	5.0	-0.7

1. At which sucrose concentration was there no change in potato mass?

2. Calculate the final mass of the potato piece in 0.2 mol/dm³ sucrose.

3. Describe the trend in mass change as sucrose concentration increases.

4. Explain why the potato lost mass in 0.6 mol/dm³ sucrose.

Answer Key

Activity 1: Nucleus (or mitochondria); controls movement of substances into and out of the cell; it has no nucleus and its DNA is not enclosed in a nucleus; nucleus

Activity 2: 80 µm; ×400; 30 µm; greater resolution, so it can show smaller structures or more detail

Activity 3: C, B, A; 2; the DNA is copied before division and each daughter cell receives an identical set of genetic material; growth (or repair/replacement of cells)

Activity 4: Net movement of particles from a region of higher concentration to a region of lower concentration; diffusion; active transport moves substances against the concentration gradient and requires energy, whereas diffusion moves down the gradient and does not require energy; osmosis

Activity 5: 0.4 mol/dm³; 5.6 g; mass change decreases as sucrose concentration increases; water moves out of the potato cells by osmosis into the more concentrated solution through partially permeable cell membranes